Philadelphia, 1844. As violent tensions escalate between nativists and Irish immigrants, Edgar Allan Poe's fears for the safety of his wife, Virginia, and mother-in-law, Muddy, are compounded when he receives a parcel of mummified bird parts. Has his nemesis returned to settle an old score? Just as odd is the arrival of Helena Loddiges, a young heiress who demands Poe's help to discover why her lover died at the city's docks on his return from an expedition to Peru. Poe is skeptical of her claims of having received messages from birds, but when Miss Loddiges is kidnapped, he and his friend C. Auguste Dupin embark on their second case, after Edgar Allan Poe and the London Monster.