At one of Timothy Leary's parties, Harvard psychology student Fitzhugh Loney and his wife, Joanie, try LSD, in this novel by the author of Water Music. The couple becomes entranced by the drug's possibilities, and their "research" turns into a free-wheeling exploration of mind expansion. With his trademark humor and pathos, T.C. Boyle follows the Loneys from Leary's notorious summer seminars in Zihuatanejo through their expulsion from Harvard and their introduction to a communal arrangement of 30 devotees living together in a 64-room mansion and devoting themselves to all kinds of experimentation and questioning. Can their sanity—and their marriage—long endure?