Like Richard Feynman in the field of physics, Dr. Robert Lefkowitz is also known for being a larger-than-life character: a self-deprecating Nobel Laureate, but always an entertaining raconteur. In addition to his time as a physician, from being a "yellow beret" in the public health corps with Dr. Anthony Fauci to his time as a cardiologist, and his transition to biochemistry, Lefkowitz has stayed in motion. Along with earnest advice on mentoring, Lefkowitz memorably discusses hobnobbing with Barack Obama, Mick Jagger, and Sting; tells what it's like behind the scenes at a Nobel ceremony; and recounts being spoofed by David Letterman.